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    의약학 >약학 >약학
  • 강의학기
    2017년 2학기
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강의계획서
강의계획서
점차 전세계의 인구가 고령화에 접어들면서 앞으로 의학시장의 규모는 지속적으로 증가할 것으로 예측되어집니다. 따라서 새로운 차세대 신약 개발의 중요성도 지속적으로 증가하고 있습니다. 본 수업에서는 신약개발에 필요한 지식인 약이 어떻게 작용하는지에 대해 이해하는 것을 목표로 합니다.
2. Introduction to drugtargets and molecularpharmacology
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차시별 강의

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1. 2. Introduction to drugtargets and molecularpharmacology Pharmacology introduction, The nature of drug targets URL
2. 2. Introduction to drugtargets and molecularpharmacology Pharmacology introduction, The nature of drug targets URL
3. 3. Molecular cloning of drug targets The relevance of recombinant DNA technology to pharmacology/drug discovery URL
4. Molecular cloning of drug targets, Agonist selectivity The cloning of drug targets URL
5. Agonist selectivity, Affinity, Efficacy Agonist selectivity, Affinity, Efficacy URL
6. Efficacy, Drugs with multiple efficacies, Quantifying agonist activity, Bi-Molecular Systems, What is drug antagonism Efficacy, Drugs with multiple efficacies, Quantifying agonist activity, Bi-Molecular Systems, What is drug antagonism URL
7. What is drug antagonism, Antagonist potency, Mechanism of receptor antagonism, Competitive and non-competitive antagonism What is drug antagonism, Antagonist potency, Mechanism of receptor antagonism, Competitive and non-competitive antagonism URL
8. Orthosteric antagonist,Competitive and non-competitive antagonism Orthosteric antagonist,Competitive and non-competitive antagonism URL
9. Characteristic properites of allosteric molecules and how they interact with proteins 1. Introduction 2. protein allosterism 3. types of allosteric modulators 4. Unique effects of allosteric modulators 5. Detecting allosterism 6. Summary URL
10. Introduction to molecularpharmacology, G-protein coupled receptors G-protein coupled receptors, Ion channels URL
11. Ion Channels, Nuclear receptors, Transporters Ion Channels, Nuclear receptors, Transporters URL
12. Molecular Pharmacology GPCR URL
13. Molecular Pharmacology GPCR URL
14. Signal transduction pathway, Desensitization and down-regulation of GPCR signaling, Constitutive GPCR activity Signal transduction pathway, Desensitization and down-regulation of GPCR signaling, Constitutive GPCR activity URL
15. Promiscuous G protein coupling, Agonist-directed signalling, Allosteric modulators of GPCR function, Pharmacological chaperones for GPCRs Promiscuous G protein coupling, Agonist-directed signalling, Allosteric modulators of GPCR function, Pharmacological chaperones for GPCRs URL
Pharmacological chaperones for GPCRs, GPCR dimerization, GPCR splice variants Pharmacological chaperones for GPCRs, GPCR dimerization, GPCR splice variants URL
GPCR dimerization Methods to study GPCR dimerzation, Homodimerization, Heterodimerization URL
Class C GPCR Class C GPCR URL
GPCR splice variants have an influence on GPCR pharmacology GPCR splice variants have an influence on GPCR pharmacology URL
GPCR drug examples, Voltage-gated ion channels GPCR drug examples, Voltage-gated ion channels URL
Voltage-gated ion channels Voltage-gated ion channels URL
Voltage-gated ion channels, Ligand-gated ion channels Voltage-gated ion channels, Ligand-gated ion channels URL
Ligand-gated ion channels Ligand-gated ion channels URL

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운영자2019-01-11 09:22
강의교재는 Molecular Pharmacology. From DNA to Drug Discovery, John Dickenson et al. 저, Wiley-Blackwell 입니다. 자세한 강의교재정보는 강의계획서를 참고하여 주시기 바랍니다.
운영자2019-01-11 09:20
KOCW입니다. 건국대학교에서는 저작권등의 사유로 강의자료를 제공하지 않습니다. 양해 부탁드립니다.
junyeop9419 2019-01-11 02:19
교재는 무엇을 사용 하시는지 알 고 싶습니다
junyeop9419 2019-01-11 02:19
강의자료를 받아 볼 수 있을까요?? ㅠㅠ

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