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모두를 위한 열린 강좌 KOCW

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강의사진
  • 주제분류
    자연과학 >생물ㆍ화학ㆍ환경 >생명공학
  • 강의학기
    2017년 1학기
  • 조회수
    9,738
  • 평점
    3.5/5.0 (2)
강의계획서
강의계획서
유전자 이상으로 생기는 질병을 DNA 또는 RNA를 사용하여 치료하려는 응용학문이다.

DNA 또는 RNA를 이용하여 질병을 일으키는 단백질의 과발현을 억제하거나, DNA 에디팅을 통하여 유전자이상을 고치는 방법 등을 학습한다.
Genetic Pharmacology I
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차시별 강의

PDF VIDEO SWF AUDIO DOC AX
1. 비디오 Genetic Pharmacology I 1. Antigene Strategy 2. Antisense Strategy URL
비디오 Genetic Pharmacology II 2. Antigene Strategy 3. Delivery Issues URL
2. 비디오 Principles of RNAi 1. Principles of RNAi Trigger Expression for Gene Therapy URL
비디오 Principles of RNAi 2. On Demand Alternative Splicing for Gene Rescue 3. Nuclease-Mediated Targeted Genetic Correction URL
3. 비디오 Small regulatory RNAs 1. Therapeutic agents based on ribonucleic acid 2. small interfering RNAs (siRNAs) URL
비디오 Small regulatory RNAs 3. microRNAs mimics (miRNA mimics) URL
4. 비디오 Gene Delivery 1. Cellular varriers to gene delivery 2. Endocytosis URL
비디오 Gene Delivery 3. Escaped from the intracellular vesicle compartment 4. Direct inoculation of DNA and RNA 5. Sonoporation, microparticles, Liposomes, cationic polymers URL
5. 비디오 CRISPR/Cas9 Genome Engineering 1. Origin of CRISPR/Cas system 2. Application of CRISPR/Cas system 3. Major components of CRISPR/Cas9 genome editing system 4. Mechanism of CRISPR/Cas9 genome editing 5. Delivery of CRISPR/Cas9 6. Advantages of CRISPR/Cas9 genome editing URL
비디오 Vectors and Gene Delivery Techniques 1 1. Vectors (Viral vector) 2. Retrovirus- and Lentivirus-Derived Vectors for Gene Transfer and Therapy URL
6. 비디오 Vectors and Gene Delivery Techniques 1 2. γ-Retrovirus- and Lentivirus-Derived Vectors for Gene Transfer and Therapy 3. Adenovirus vectors URL
비디오 Vectors and Gene Delivery Techniques 1 3. Adenovirus, Adeno-Associated Virus (AAV) Vectors 4. Herpes Simplex Virus (HSV-1)-Based Vectors: Applications for Gene Transfer, Gene Therapy, Cancer Virotherapy and Vaccination URL
7. 비디오 Vectors and Gene Delivery Techniques 2 1. Vectors (Non-viral vector) 2. Macromolecular Conjugates for Non-Viral Nucleic Acid Delivery 3. Auto-Associative Lipid-Based Systems for Non-Viral Nucleic Acid Delivery 4. Electrotransfer/Electroporation for Non-Viral Nucleic Acid Delivery URL
8. 비디오 Therapeutic Applications 1 1. Oncolytic Adenoviruses for Cancer Gene Therapy URL
9. 비디오 Therapeutic Applications 1 2. Progress in DNA Vaccine Approaches for Cancer Immunotherapy URL
10. 비디오 Therapeutic Applications 2 1. Gene Therapy of the Beta-Hemoglobinopathies 2. Gene Therapy for Hemophilia A and B URL
비디오 Therapeutic Applications 2 3. Experimental and Clinical Ocular Gene Therapy 4. Gene Therapy of Neurological Diseases URL
11. 비디오 Gene Vector Production 1. Production and Purification of Viral Vectors URL
비디오 Gene Vector Production 2. Safety Considerations Related to Gene Vector Production URL
12. 비디오 Clinical application of gene therapy: General considerations 1. Number/ phases of clinical trials 2. Disease addressed by gene therapy clinical trials 3. Therapeutic genes used in the clinical trials 4. Modality of therapeutic gene delivery in gene therapy clinical trials URL
13. 비디오 Ethical and social problems of gene therapy 1. Safety of clinical experimentation 2. Ethical and social problems of gene therapy 3. Regulation and guidelines of gene therapy URL

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