융합 생체막 생물학

강의상세

생체막 시스템에 대한 기본지식과 첨단수준의 topic을 다룸. Topic은 지질대사와 이동, 지질 신호전달, 세포막 이동, 생체막 도메인, 막단백질, 생체막-세포골격 상호작용, 생체막-단백질 상호작용, 세포간 상호작용 및 생체막 연구에 따른 방법론을 포함할 것이다.

Introduction to biological membranes

1.	Introduction to biological membranes	General description of cell membrane models and their components, lipids and proteins
2.	The structures and properties of membrane lipids	Description of structures of major mammalian lipids and their physical and chemical properties
3.	Lipid biosynthesis and transport	Description of the biosynthesis of major membrane lipids, different mechanisms of their transport to target membranes, and different lipid compositions of various organelle membranes.
4.	Cell signaling	General description of cellular signaling mechanisms with an emphasis on the role of proteins as binary signaling switches
5.	Lipid signaling1	Description of cell signaling by lipids, including phosphoinositides
6.	Lipid signaling2	Description of lipid signaling enzymes, including phospholipases, lipid kinases, lipid phosphatases
7.	Lipid signaling3	Description of cell signaling by phosphatidylinositol-(4,5)-bisphosphate and eicosanoids
8.	Membrane-binding proteins and membrane-protein interactions	General description of membrane proteins, including integral and peripheral membrane proteins and the mechanisms by which cellular proteins are recruited to the membranes
9.	Lipid modification of proteins	Description of the regulation of membrane interaction of proteins by various lipidation
10.	Membrane compartmentalization	Description of the formation of membrane domains, including lipid rafts, and its potential roles in cell regulation