Transmission electron microscopy with nano-analytical capabilities represents the single most high-resolution experimental method available for the study of the geometry of atom arrangements in solids, and the distribution of chemical species in solids. Most research literature discussing deformation or chemical reaction mechanisms in solids at or near the atomic level is written from the electron microscopy viewpoint, and an increasing amount of research of this type is being carried out on electronic materials. The lecture course is sufficient preparation for those students who expect to interact with solid-state scientists who study the atomic scale structure of matter.