약물전달학

건국대학교
신하연

페이스북 트위터 카카오톡 네이버밴드 링크복사

주제분류

의약학 >약학 >약학
강의학기

2017년 2학기

조회수

12,023

강의계획서

This course will provide students with a basic understanding of principles and applications of controlled drug delivery systems. To this end, it will focus on topics including physicochemical and biological barriers, drug delivery pathways, metabolism, drug formulation, pharmacokinetic and pharmacodynamic issues. It will expand the coverage to reflect latest updates and advances in materials for delivery vehicles, drug delivery approaches, and therapeutics.

수강안내 및 수강신청
※ 수강확인증 발급을 위해서는 수강신청이 필요합니다

Factors that Impact the Developability of Drug Candidates

차시별 강의

1.	Factors that Impact the Developability of Drug Candidates	1. Challenges Facing the Pharmaceutical Industry 2. Factors that Impact Developability 3. Remarks on Developability 4. Drug Delivery Factors that Impact Developability
2.	Physiological, Biochemical, andChemical Barriers to Oral Drug Delivery	Introduction 1. Physiological Barriers to Drug Delivery 2. Biochemical Barriers to Drug Delivery
3.	Physiological, Biochemical, and Chemical Barriers to Oral Drug Delivery	2. Biochemical Barriers to Drug Delivery 3. Chemical Barriers to Drug Delivery 4. Drug Modifications to Enhance Transport Across Biological Barriers
4.	PhysicochemicalProperties, Formulation, and Drug Delivery	1. Physicochemical Properties 2. Formulations
5.	PhysicochemicalProperties, Formulation, and Drug Delivery	3. Drug Delivery 1. Target Bioavailability
6.	Targeted Bioavailability: A Fresh Look at Pharmacokinetic and Pharmacodynamic Issues in Drug Discovery and Development	1. Target Bioavailability 2. Drug Delivery Trends and Targets Related to PK and PD 3. PK？PD in Drug Discovery and Development 4. Source of Variability of Drug Response
7.	Targeted Bioavailability :A Fresh Look at Pharmacokinetic and Pharmacodynamic Issues in Drug Discovery and Development	4. Source of Variability of Drug Response 5. Recent Development and Issues of Bio- Analytical Methodology 6.Mechanistic PK？PD Models
8.	The Role of Transporters in Drug Delivery and Excretion	1. Drug Transport in Absorption and Excretion 2. ABC (ATP-Binding Cassette) Transporter Family
9.	The Role of Transporters in Drug Delivery and Excretion	3. SlC (Solute Carrier) Transporter Family
10.	Intracellular Deliveryand Disposition of Small-Molecular Weight Drugs	1. The Relationship between the Intracellular Distribution of a Drug and its Activity 2. The Relationship between the Intracellular Distribution of a Drug and its Pharmacokinetic Properties 3. Overview of Approaches to Study Intracellular Drug Disposition 4. The Accumulation of Drugs in Mitochondria, Lysosomes, and Nuclei
11.	Intellectual Property and Regulatory Issues inDrug Delivery Research	1. Pharmaceutical Patents 2. Statutory Requirements for Obtaining a Patent 3. Patent Procurement Strategies
12.	Intellectual Property and Regulatory Issues inDrug Delivery Research	4. Regulatory Regime 5. FDA Market Exclusivities 6. Regulatory and Patent Law Linkage
13.	Presystemic and First-Pass Metabolism	1. Hepatic First-Pass Metabolism
14.	Pulmonary DrugDelivery: PharmaceuticalChemistry and Aerosol Technology	1. Aerosol Technology 2. Disease Therapy
15.	Pulmonary DrugDelivery: PharmaceuticalChemistry and Aerosol Technology	1. Aerosol Technology 2. Disease Therapy
	Pulmonary DrugDelivery: PharmaceuticalChemistry and Aerosol Technology	2. Disease Therapy 3. Formulation Variables 4. Future Developments
	Transdermal Delivery of Drugs Using Patchesand Patchless Delivery Systems	1. Transdermal Patch Delivery Systems 2. Patchless Transdermal Drug Delivery Systems
	Transdermal Delivery of Drugs Using Patchesand Patchless DeliverySystems, Prodrug Approaches toDrug Delivery	2. Patchless Transdermal Drug Delivery Systems 3. Recent Advances in Transdermal Drug Delivery 1. Basic Concepts: Definition and Applications
	Prodrug Approaches to Drug Delivery	1. Basic Concepts: Definition and Applications 2. Prodrug Design Considerations
	Nanoparticles as DrugDelivery Vehicles	1. General DDV Properties 2. Organic DDVs 3. Inorganic DDVs: Metal- and Silica ]Based Systems
	Nanoparticles as DrugDelivery Vehicles	1. General DDV Properties 2. Organic DDVs 3. Inorganic DDVs: Metal- and Silica ]Based Systems